Training to muscular failure maximizes muscle hypertrophy

The claim that taking every set to complete muscular failure (inability to complete another rep) is necessary or optimal for maximizing muscle growth compared to stopping short of failure.

failurehypertrophymuscle growthintensity
3 studies weighed Updated

Evidence Breakdown

1 PRO
1 AGAINST
1 NEUTRAL

Based on 3 studies

Evidence map

For & against, at a glance

Pro Con Neutral
60.3% confidence
Claim
1 1 1
Meta-Analysis Pro
Grgic J et al. · 2022
Sports Medicine

Meta-analysis found a small but statistically significant benefit of training to failure for muscle hypertrophy compared to not training to failure. The effect was more pronounced in untrained individuals and when fewer sets were performed.

0.85

Meta-analysis found a small but statistically significant benefit of training to failure for muscle hypertrophy compared to not training to failure. The effect was more pronounced in untrained individuals and when fewer sets were performed.

Design Meta-Analysis (1.0) × quality 0.85 = impact 0.85

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Systematic Review Neutral
Santos WDN et al. · 2022
Frontiers in Physiology

Systematic review found that training to failure may provide a small hypertrophy advantage when training volume is equated, but the practical significance is questionable. Training close to failure (1-3 reps in reserve) appears sufficient for most trainees.

0.68

Systematic review found that training to failure may provide a small hypertrophy advantage when training volume is equated, but the practical significance is questionable. Training close to failure (1-3 reps in reserve) appears sufficient for most trainees.

Design Systematic Review (0.9) × quality 0.75 = impact 0.68

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RCT Con
Carroll KM et al. · 2019
Journal of Strength and Conditioning Research

RCT in trained lifters found that training to failure did not produce superior hypertrophy compared to submaximal training when volume was matched. Training to failure also resulted in greater fatigue accumulation, potentially limiting total training volume over time.

0.56

RCT in trained lifters found that training to failure did not produce superior hypertrophy compared to submaximal training when volume was matched. Training to failure also resulted in greater fatigue accumulation, potentially limiting total training volume over time.

Design RCT (0.8) × quality 0.70 = impact 0.56

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Evidence

PRO (1)

PRO Meta-Analysis 0.85 Grgic J, Schoenfeld BJ et al. (2022)

Meta-analysis found a small but statistically significant benefit of training to failure for muscle hypertrophy compared to not training to failure. The effect was more pronounced in untrained individuals and when fewer sets were performed.

Sports Medicine

DOI: 10.1007/s40279-021-01586-w

AGAINST (1)

AGAINST RCT 0.70 Carroll KM, Bazyler CD et al. (2019)

RCT in trained lifters found that training to failure did not produce superior hypertrophy compared to submaximal training when volume was matched. Training to failure also resulted in greater fatigue accumulation, potentially limiting total training volume over time.

Journal of Strength and Conditioning Research

DOI: 10.1519/JSC.0000000000002957

NEUTRAL (1)

NEUTRAL Systematic Review 0.75 Santos WDN, Vieira CA et al. (2022)

Systematic review found that training to failure may provide a small hypertrophy advantage when training volume is equated, but the practical significance is questionable. Training close to failure (1-3 reps in reserve) appears sufficient for most trainees.

Frontiers in Physiology

DOI: 10.3389/fphys.2022.981tried