FitProven
Evidence Breakdown
Based on 3 studies
Evidence map
For & against, at a glance
Systematic Review
Pro
Dattilo M et al. · 2011Medical HypothesesSystematic review examining the relationship between sleep and muscle recovery. The authors found that sleep deprivation decreases the activity of protein synthesis pathways and increases degradation pathways, favoring muscle loss. Growth hormone, which is predominantly secreted during deep sleep, plays a critical role in tissue repair and muscle growth.
0.79
Systematic review examining the relationship between sleep and muscle recovery. The authors found that sleep deprivation decreases the activity of protein synthesis pathways and increases degradation pathways, favoring muscle loss. Growth hormone, which is predominantly secreted during deep sleep, plays a critical role in tissue repair and muscle growth.
Design Systematic Review (0.9) × quality 0.88 = impact 0.79
View sourceRCT
Pro
Leproult R & Van Cauter E · 2011JAMAControlled study restricting sleep to 5 hours per night for one week in young healthy men. Daytime testosterone levels decreased by 10-15% compared to the rested condition. Since testosterone is a primary anabolic hormone supporting muscle growth, the authors concluded that chronic sleep restriction could significantly impair muscle-building capacity.
0.66
Controlled study restricting sleep to 5 hours per night for one week in young healthy men. Daytime testosterone levels decreased by 10-15% compared to the rested condition. Since testosterone is a primary anabolic hormone supporting muscle growth, the authors concluded that chronic sleep restriction could significantly impair muscle-building capacity.
Design RCT (0.8) × quality 0.82 = impact 0.66
View sourceNarrative Review
Pro
Lamon S et al. · 2021Sleep Medicine ReviewsComprehensive review synthesizing evidence on how sleep loss affects skeletal muscle physiology. The authors found consistent evidence that sleep restriction impairs muscle protein synthesis, alters the hormonal environment (reducing testosterone and IGF-1, elevating cortisol), and increases systemic inflammation. All of these pathways are detrimental to muscle growth and recovery.
0.23
Comprehensive review synthesizing evidence on how sleep loss affects skeletal muscle physiology. The authors found consistent evidence that sleep restriction impairs muscle protein synthesis, alters the hormonal environment (reducing testosterone and IGF-1, elevating cortisol), and increases systemic inflammation. All of these pathways are detrimental to muscle growth and recovery.
Design Narrative Review (0.3) × quality 0.78 = impact 0.23
View sourceSystematic Review
Pro
Dattilo M et al. · 2011Medical HypothesesSystematic review examining the relationship between sleep and muscle recovery. The authors found that sleep deprivation decreases the activity of protein synthesis pathways and increases degradation pathways, favoring muscle loss. Growth hormone, which is predominantly secreted during deep sleep, plays a critical role in tissue repair and muscle growth.
0.79
Systematic review examining the relationship between sleep and muscle recovery. The authors found that sleep deprivation decreases the activity of protein synthesis pathways and increases degradation pathways, favoring muscle loss. Growth hormone, which is predominantly secreted during deep sleep, plays a critical role in tissue repair and muscle growth.
Design Systematic Review (0.9) × quality 0.88 = impact 0.79
View sourceRCT
Pro
Leproult R & Van Cauter E · 2011JAMAControlled study restricting sleep to 5 hours per night for one week in young healthy men. Daytime testosterone levels decreased by 10-15% compared to the rested condition. Since testosterone is a primary anabolic hormone supporting muscle growth, the authors concluded that chronic sleep restriction could significantly impair muscle-building capacity.
0.66
Controlled study restricting sleep to 5 hours per night for one week in young healthy men. Daytime testosterone levels decreased by 10-15% compared to the rested condition. Since testosterone is a primary anabolic hormone supporting muscle growth, the authors concluded that chronic sleep restriction could significantly impair muscle-building capacity.
Design RCT (0.8) × quality 0.82 = impact 0.66
View sourceNarrative Review
Pro
Lamon S et al. · 2021Sleep Medicine ReviewsComprehensive review synthesizing evidence on how sleep loss affects skeletal muscle physiology. The authors found consistent evidence that sleep restriction impairs muscle protein synthesis, alters the hormonal environment (reducing testosterone and IGF-1, elevating cortisol), and increases systemic inflammation. All of these pathways are detrimental to muscle growth and recovery.
0.23
Comprehensive review synthesizing evidence on how sleep loss affects skeletal muscle physiology. The authors found consistent evidence that sleep restriction impairs muscle protein synthesis, alters the hormonal environment (reducing testosterone and IGF-1, elevating cortisol), and increases systemic inflammation. All of these pathways are detrimental to muscle growth and recovery.
Design Narrative Review (0.3) × quality 0.78 = impact 0.23
View sourceTap any node to expand its detail.
Evidence
PRO (3)
PRO Systematic Review 0.88 Dattilo M, Antunes HK et al. (2011)
Systematic review examining the relationship between sleep and muscle recovery. The authors found that sleep deprivation decreases the activity of protein synthesis pathways and increases degradation pathways, favoring muscle loss. Growth hormone, which is predominantly secreted during deep sleep, plays a critical role in tissue repair and muscle growth.
Medical Hypotheses
PRO RCT 0.82 Leproult R, Van Cauter E (2011)
Controlled study restricting sleep to 5 hours per night for one week in young healthy men. Daytime testosterone levels decreased by 10-15% compared to the rested condition. Since testosterone is a primary anabolic hormone supporting muscle growth, the authors concluded that chronic sleep restriction could significantly impair muscle-building capacity.
JAMA
PRO Narrative Review 0.78 Lamon S, Morabito A et al. (2021)
Comprehensive review synthesizing evidence on how sleep loss affects skeletal muscle physiology. The authors found consistent evidence that sleep restriction impairs muscle protein synthesis, alters the hormonal environment (reducing testosterone and IGF-1, elevating cortisol), and increases systemic inflammation. All of these pathways are detrimental to muscle growth and recovery.
Sleep Medicine Reviews